Mesothelioma Treatment Centers

Top mesothelioma cancer centers and hospitals offer specialized care focused on improving patient outcomes.

These centers provide advanced treatment options from experienced mesothelioma specialists. They offer personalized treatment plans and access to the latest therapies to help extend survival and enhance quality of life.

Below, you’ll find mesothelioma treatment centers from across the United States. Many feature dedicated mesothelioma programs. We also provide guidance on why receiving treatment at a cancer center specializing in mesothelioma matters, and how to choose the right center for you.

Top Mesothelioma Treatment Centers in the U.S.

Leading mesothelioma treatment centers are located nationwide, often within major hospitals, cancer institutes, and VA medical systems. These specialized facilities offer access to experienced mesothelioma doctors, advanced technology, and innovative clinical trials. Receiving care at one of these centers can improve treatment outcomes and may help patients live longer.

The following hospitals earned top spots for cancer care in the 2025–2026 U.S. News & World Report rankings:

• Dana-Farber Brigham Cancer Center: Boston, MA
  Home to the International Mesothelioma Program, one of the world's leading centers for mesothelioma care.
• Hospital of the University of Pennsylvania - Penn Presbyterian: Philadelphia, PA
  Penn Medicine’s Mesothelioma and Pleural Disease Program specializes in treating mesothelioma and related pleural conditions.
• Massachusetts General Hospital: Boston, MA
  Treats mesothelioma, lung cancer and other thoracic cancers through The Center for Thoracic Cancers.
• Mayo Clinic Cancer Center: Rochester, MN
  The Mayo Clinic Thoracic Surgery Division offers patients comprehensive, team-based care tailored to each stage of mesothelioma treatment.
• Mayo Clinic Hospital: Phoenix, AZ
  Mesothelioma patients can be treated in Phoenix or at the Scottsdale campus. Clinical trials may be available.
• Mount Sinai Hospital: New York, NY
  National Cancer Institute-designated center with thoracic oncology expertise.
• OHSU Knight Cancer Institute: Portland, OR
  NCI-designated Comprehensive Cancer Center, offering a team-based approach for mesothelioma treatment.
• Stanford Health Care - Stanford Hospital: Palo Alto, CA
  Offers treatment of malignant pleural mesothelioma through the Thoracic and Lung Cancer Program.
• University of Texas MD Anderson Cancer Center: Houston, TX
  Renowned for mesothelioma treatment with a dedicated Thoracic Center and robust clinical trial program.
• UCLA Medical Center: Los Angeles, CA
  Jonsson Comprehensive Cancer Center at UCLA is known for innovative lung-sparing surgeries and mesothelioma treatment programs.

Some mesothelioma treatment centers have earned a designation from the National Cancer Institute (NCI). This honor recognizes their leadership in cancer research and their commitment to providing innovative care.

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Pleural Mesothelioma Cancer Centers

Pleural mesothelioma, the most common form of this cancer, accounts for 80-90% of all mesothelioma diagnoses. It develops in the lining of the lungs known as the pleura. It is treated at select centers with dedicated expertise and latest treatments for managing the disease.

Some of the top cancer centers for treating pleural mesothelioma include:

• CHI Health Good Samaritan Cancer Center: Kearney, NE
• City of Hope Comprehensive Cancer Center: Duarte, CA
• Dana-Farber Brigham Cancer Center: Boston, MA
• The Lung Institute at Baylor College of Medicine: Houston, TX
• The Moffitt Cancer Center: Tampa, FL
• University of Texas MD Anderson Cancer Center: Houston, TX

Peritoneal Mesothelioma Cancer Centers

Peritoneal mesothelioma, the second most common type of the disease, accounts for 10-15% of cases. It develops in the abdominal lining known as the peritoneum. A number of cancer centers across the country offer specialized programs dedicated to treating this form of mesothelioma.

Some of the top cancer centers for treating peritoneal mesothelioma include:

• Mount Sinai Hospital: New York, NY
• Ridley-Tree Cancer Center: Santa Barbara, CA
• Sylvester Comprehensive Cancer Center: Miami, FL
• Taussig Cancer Institute at Cleveland Clinic: Cleveland, OH
• University of Chicago Medicine Comprehensive Cancer Center: Chicago, IL
• Vanderbilt University Medical Center: Nashville, TN

VA Treatment Centers

A significant number of mesothelioma cases occur among veterans. While veterans can seek care at any of the centers mentioned above, several VA medical centers also specialize in mesothelioma treatment. These VA centers understand the unique needs of those exposed to asbestos during military service and are familiar with the specific care and resources veteran patients require. Travel expenses like transportation and lodging may also be covered. Many of these facilities collaborate with mesothelioma programs outside of VA centers, ensuring veterans have access to advanced, cutting-edge treatments.

Some leading VA mesothelioma treatment centers include:

• Atlanta VA Medical Center: Decatur, GA
• Bruce W. Carter VA Medical Center: Miami, FL
• VA Boston Healthcare System: Boston, MA
• West Los Angeles VA Medical Center: Los Angeles, CA
• Michael E. DeBakey VA Medical Center (MEDVAMC): Houston, TX

Specialized Mesothelioma Treatment: Why It Matters

Mesothelioma is a rare, aggressive cancer. About 3,000 people in the United States are diagnosed each year. Symptoms often take decades to appear after asbestos exposure and are frequently mistaken for other illnesses. Because many general oncologists have limited experience with this disease, patients often benefit from care at specialized centers where doctors regularly treat mesothelioma.

Why Choose a Specialized Mesothelioma Treatment Center?

Selecting a cancer center that specializes in mesothelioma care may improve diagnostic accuracy, provide personalized treatment plans, and offer access to therapies that may improve outcomes and quality of life for patients.

• Prompt and Accurate Diagnosis: Mesothelioma symptoms often mimic other illnesses and can be misdiagnosed. Specialists know what to look for and can confirm your diagnosis.
• Personalized and Advanced Treatment Plans: Patients benefit from having a multidisciplinary team of doctors that collaborate on an individualized treatment plan tailored to each patient’s needs. Type and stage of mesothelioma are factors that help determine treatment options.
• Specialized Care Can Help Improve Life Expectancy: Because mesothelioma is aggressive, starting effective treatment early is essential to helping patients live longer.

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How to Select a Treatment Center That’s Right for You

Choosing the right mesothelioma treatment center is a personal and important decision for patients and their loved ones. Consider these key factors when making your choice:

• Mesothelioma Specialists: Choose doctors that have expertise in diagnosing and treating mesothelioma.
• Comprehensive Treatment Options: Look for centers offering patient-focused, multimodal treatment, including surgery, chemotherapy, radiation, emerging therapies, cutting-edge clinical trials, and palliative care.
• Special Designations: Seek treatment centers recognized by reputable organizations that meet the quality standards of one or more accreditation agencies, such as the National Cancer Institute (NCI), Commission on Cancer (COC), or National Comprehensive Cancer Network (NCCN).
• Dedicated Mesothelioma Programs: Find facilities with specialized programs that focus on treatment and support for specific mesothelioma diagnoses.
• Costs & Financial Assistance: Understand out-of-pocket expenses like travel and lodging. Ask about travel grants, housing help, and free clinical trials.
• Support Services: Social workers, counselors, and patient navigators can help address emotional, logistical, and practical needs for patients and family members.

Common Questions

What is the number one mesothelioma cancer treatment center?

Some of the best treatment centers and hospitals for mesothelioma include University of Texas MD Anderson Cancer Center in Houston, TX, Dana-Farber Brigham Cancer Center in Boston, MA, and Mount Sinai Hospital in New York, NY.

The best hospital for mesothelioma patients meets your specific needs, offers effective treatments, access to top specialists (oncologists, thoracic surgeons, etc.), and accreditations such as an NCI-designation, along with clinical trials and supportive care services.

What is the difference between a cancer center and a comprehensive cancer center?

An NCI-Designated Cancer Center meets national standards for cancer research, prevention, and treatment, sometimes focusing on specific areas like clinical trials or population studies. A Comprehensive Cancer Center holds a higher NCI designation. The requirements are the most rigorous and must show expertise in these three areas: laboratory, clinical and behavioral, and population-based research. These centers often work with major universities, to provide the most complete cancer care possible.

Among the top NCI-designated Comprehensive Cancer Centers specializing in mesothelioma are:

• Dana-Farber/Harvard Cancer Center, Boston, Massachusetts
• Moffitt Cancer Center, Tampa, Florida
• UCLA Health Jonsson Comprehensive Cancer Center, Los Angeles, California
• Mayo Clinic Cancer Center, Rochester, Minnesota

Do all cancer centers and hospitals treat mesothelioma?

No. Mesothelioma is a rare and aggressive cancer that requires specialized treatment from experienced specialists. Many hospitals may have limited experience with this disease and could misdiagnose or delay treatment. Top mesothelioma cancer centers and hospital have doctors who specialize in treating asbestos-related diseases, access to the latest therapies, clinical trials, and comprehensive support services.